个人基本信息
姓名：刘薇
性别：女
性别：女
职称：副教授、硕士生导师
邮编：450046
通讯地址：中国·河南·郑州市郑东新区平安大道218号 河南农业大学生命科学学院
通讯地址：中国·河南·郑州市郑东新区平安大道218号 河南农业大学生命科学学院
E-mail：liuv@henau.edu.cn
个人简介
2023-05至今，河南农业大学 动物学系 副教授；
2017-09至2023-05，河南农业大学 动物学系 讲师；
2013-09至2017-07, 中国科学院大学, 微生物研究所, 博士；
2010-09至2013-07, 天津科技大学, 食品工程与生物技术学院, 硕士；
2006-09至2010-07, 内蒙古科技大学, 350vip88888新葡的京集团, 学士；
教授课程
本科生：《发育生物学》、《细胞工程》
研究生：《发育生物学》、《病毒学研究进展》
研究生：《发育生物学》、《病毒学研究进展》
主要研究领域
宿主抗病毒的天然免疫信号通路的研究；动物病毒与宿主相互作用的机制研究。
近五年发表论著
1. Cui Yuan, Zhenling Ma, Jiufeng Xie, Wenqing Li, Lijuan Su, Guozhi Zhang, Jun Xu, Yaru Wu, Min Zhang，Wei Liu∗. The role of cell death in SARS-CoV-2 infection. Signal Transduction and Targeted Therapy，2023，20;8(1):357.
2. Wei Liu, Lei Wang, Jiajia Zhang, Kun Cheng, Wenming Zheng，Zhenling Ma. CC Chemokine 2 Promotes Ovarian Cancer Progression through the MEK/ERK/MAP3K19 Signaling Pathway. International Journal of Molecular Sciences，2023, 24, 10652.
3. Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Xixi Shi, Menghao Zhang, Wenwen Zhang, Wei Liu∗. The role of cyclophilins in viral infection and the immune response. Journal of Infection, 2022, 85:365–373.
4. Yaru Wu, Min Zhang, Zhenling Ma, Cui Yuan, Wenqing Li, Yanyan Zhang, Lijuan Su, Jun Xu, Wei Liu*. Progress of cGAS-STING Signaling in Response to SARS-CoV-2 Infection. Frontiers in Immunology, 2022, 13.
5. Wei Liu*, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang，Pengtao Jiao*. MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway. Cell Communication and Signaling, 2022,20:103.
6. Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Wenwen Zhang, Menghao Zhang, Xixi Shi, Wenqing Li，Wei Liu*. Cyclophilin A regulates the apoptosis of A549 cells by stabilizing Twist1 protein. Journal of Cell Science, 2022, 135, jcs259018.
7. Zhenling Ma, Wenwen Zhang, Wenhui Fan, Yaru Wu, Menghao Zhang, Jun Xu，Wenqing Li, Lei Sun, Wenjun Liu, Wei Liu*. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses, International Immunopharmacology, 2021, 90:107152.
8. Wenwen Zhang, Zhenling Ma, Yaru Wu, Xixi Shi, Yanyan Zhang Min Zhang, Menghao Zhang, Lei Wang, Wei Liu*. SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3. Cytokine, 2021, 148x155697.
9. Zhenling Ma, Wenwen Zhang, Yaru Wu, Menghao Zhang, Lei Wang, Yihan Wang, Yi Wang, Wei Liu*. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway, Bioscience Reports, 2021, 29; 41(1): BSR20203219.
10. Wei Liu, Lei Wang, Jiajia Zhang, Liuhui Qiao, Yiqing Liu, Xinke Yang, Jinghua Zhang, Wenming Zheng, Zhenling Ma*. Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer, 3 Biotech, 2021, 11(1): 8.
11. 岳岩磊, 张稳稳, 张梦豪, 刘薇*. Cyclophilin A 在病毒感染中的作用研究进展. 中国免疫学杂志, 2021, 37: 1012-1021.
12. 马振玲, 王雷,乔柳惠 , 刘薇*. 小鼠 CCL2 蛋白原核表达及纯化分析.生物学杂志，2021,38（6）: 20-24.
13. 张稳稳，岳岩磊，马振玲，姚文，杨国庆，刘薇*. FoxO1 在病毒感染和炎症发生中的作用. 病毒学报，2021，37（3）: 726-731.
14. Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun 1,2 *Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses. 2017, 6: e24425.
2. Wei Liu, Lei Wang, Jiajia Zhang, Kun Cheng, Wenming Zheng，Zhenling Ma. CC Chemokine 2 Promotes Ovarian Cancer Progression through the MEK/ERK/MAP3K19 Signaling Pathway. International Journal of Molecular Sciences，2023, 24, 10652.
3. Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Xixi Shi, Menghao Zhang, Wenwen Zhang, Wei Liu∗. The role of cyclophilins in viral infection and the immune response. Journal of Infection, 2022, 85:365–373.
4. Yaru Wu, Min Zhang, Zhenling Ma, Cui Yuan, Wenqing Li, Yanyan Zhang, Lijuan Su, Jun Xu, Wei Liu*. Progress of cGAS-STING Signaling in Response to SARS-CoV-2 Infection. Frontiers in Immunology, 2022, 13.
5. Wei Liu*, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang，Pengtao Jiao*. MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway. Cell Communication and Signaling, 2022,20:103.
6. Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Wenwen Zhang, Menghao Zhang, Xixi Shi, Wenqing Li，Wei Liu*. Cyclophilin A regulates the apoptosis of A549 cells by stabilizing Twist1 protein. Journal of Cell Science, 2022, 135, jcs259018.
7. Zhenling Ma, Wenwen Zhang, Wenhui Fan, Yaru Wu, Menghao Zhang, Jun Xu，Wenqing Li, Lei Sun, Wenjun Liu, Wei Liu*. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses, International Immunopharmacology, 2021, 90:107152.
8. Wenwen Zhang, Zhenling Ma, Yaru Wu, Xixi Shi, Yanyan Zhang Min Zhang, Menghao Zhang, Lei Wang, Wei Liu*. SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3. Cytokine, 2021, 148x155697.
9. Zhenling Ma, Wenwen Zhang, Yaru Wu, Menghao Zhang, Lei Wang, Yihan Wang, Yi Wang, Wei Liu*. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway, Bioscience Reports, 2021, 29; 41(1): BSR20203219.
10. Wei Liu, Lei Wang, Jiajia Zhang, Liuhui Qiao, Yiqing Liu, Xinke Yang, Jinghua Zhang, Wenming Zheng, Zhenling Ma*. Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer, 3 Biotech, 2021, 11(1): 8.
11. 岳岩磊, 张稳稳, 张梦豪, 刘薇*. Cyclophilin A 在病毒感染中的作用研究进展. 中国免疫学杂志, 2021, 37: 1012-1021.
12. 马振玲, 王雷,乔柳惠 , 刘薇*. 小鼠 CCL2 蛋白原核表达及纯化分析.生物学杂志，2021,38（6）: 20-24.
13. 张稳稳，岳岩磊，马振玲，姚文，杨国庆，刘薇*. FoxO1 在病毒感染和炎症发生中的作用. 病毒学报，2021，37（3）: 726-731.
14. Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun 1,2 *Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses. 2017, 6: e24425.
科研项目
1、亲环素A对NLRP3炎症小体介导IL-1β产生的调控机制，国家自然科学基金， 2019.1-2021.12，主持
2、CyclophilinA对TLR3介导的IFN产生的调控机制、河南农业大学青年英才项目， 2018.06-2023.6，主持
2、CyclophilinA对TLR3介导的IFN产生的调控机制、河南农业大学青年英才项目， 2018.06-2023.6，主持
